Journal of Clinical Sciences

CLINICAL REVIEW
Year
: 2020  |  Volume : 17  |  Issue : 4  |  Page : 93--99

Molecular diagnosis of tuberculosis with emphasis on Xpert Mycobacterium tuberculosis assay – Clinical review


Gajanan S Gaude, Samskruti Vishwanath 
 Department of Pulmonary Medicine, J. N. Medical College, KAHER's, Belgaum, Karnataka, India

Correspondence Address:
Dr. Gajanan S Gaude
Department of Pulmonary Medicine, J. N. Medical College, KAHER's, Belgaum - 590 010, Karnataka
India

Tuberculosis (TB), due to Mycobacterium tuberculosis(MTB), remains a major public health issue. It causes ill health for approximately 10 million people each year and is one of the top ten causes of death worldwide. For the past 5 years, it has been the leading cause of death from a single infectious agent, ranking above HIV/AIDS. Effective diagnosis of pulmonary TB requires the availability – on a global scale – of standardized, easy-to-use, and robust diagnostic tool that would allow the direct detection of both the MTB complex and the resistance to key drugs, such as rifampicin. The latter result can serve as a marker for multidrug-resistant (MDR) MTB and has been reported in >95% of the MDR-TB isolates. Here, we review some of the recent molecular methods in the diagnosis of TB.


How to cite this article:
Gaude GS, Vishwanath S. Molecular diagnosis of tuberculosis with emphasis on Xpert Mycobacterium tuberculosis assay – Clinical review.J Clin Sci 2020;17:93-99


How to cite this URL:
Gaude GS, Vishwanath S. Molecular diagnosis of tuberculosis with emphasis on Xpert Mycobacterium tuberculosis assay – Clinical review. J Clin Sci [serial online] 2020 [cited 2021 Jan 20 ];17:93-99
Available from: https://www.jcsjournal.org/article.asp?issn=2468-6859;year=2020;volume=17;issue=4;spage=93;epage=99;aulast=Gaude;type=0