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 Table of Contents  
LETTER TO EDITOR
Year : 2018  |  Volume : 15  |  Issue : 4  |  Page : 213

Infantile hemangioendothelioma of the liver in a Nigerian newborn: A case report


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication3-Dec-2018

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcls.jcls_78_17

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How to cite this article:
Al-Mendalawi MD. Infantile hemangioendothelioma of the liver in a Nigerian newborn: A case report. J Clin Sci 2018;15:213

How to cite this URL:
Al-Mendalawi MD. Infantile hemangioendothelioma of the liver in a Nigerian newborn: A case report. J Clin Sci [serial online] 2018 [cited 2019 Jan 23];15:213. Available from: http://www.jcsjournal.org/text.asp?2018/15/4/213/246770



Sir,

I have two comments on the case report by Ezenwa et al. on the hemangioendothelioma (HE) of the liver in a 22-day-old Nigerian neonate.[1]

First, apart from opportunistic infections, it is obvious that individuals infected with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) are more vulnerable to a wide range of tumors, including vascular one. To my knowledge, Nigeria is among Sub-Saharan countries markedly affected with HIV/AIDS. Although no recent data are yet present on the exact prevalence of pediatric HIV infection, the available data pointed out that 3% of Nigerian women who were HIV negative at booking visit tested positive (seroconverted) to HIV.[2] The HIV status of the mother of the studied neonate was not determined. I presume that some sort of vertical HIV transmission to the neonate ought to be considered by the authors. Hence, the estimations of CD4 count and viral overload in the studied neonate were envisaged. If these measurements were done and they revealed underling HIV infection, the case in question could truly be considered a novel case report in Nigeria as HIV-associated pediatric HE has been rarely reported in the literature.[3]

Second, regrettably, regular follow-up of the studied neonate could not be guaranteed due to family financial constraints. This point is of paramount importance as hepatic angiosarcoma has been reported developing in a pediatric patient who had been earlier diagnosed and was being treated for hepatic HE.[4]

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Ezenwa BN, Nwaogazie U, Akintan P, Fajolu I, Ezeaka C, Adeniyi O. Infantile hemangioendothelioma of the liver in a Nigerian newborn: A case report. J Clin Sci 2017;14:144-7.  Back to cited text no. 1
  [Full text]  
2.
Nyoyoko NP, Umoh AV. The prevalence and determinants of HIV seroconversion among booked ante natal clients in the University of Uyo teaching hospital, Uyo Akwa Ibom State, Nigeria. Pan Afr Med J 2016;25:247.  Back to cited text no. 2
    
3.
Paul SR, Hurford MT, Miettinen MM, Aronoff SC, Delvecchio M, Grewal H, et al. Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS). Pediatr Blood Cancer 2008;50:663-5.  Back to cited text no. 3
    
4.
Kamath SM, Mysorekar VV, Kadamba P. Hepatic angiosarcoma developing in an infantile hemangioendothelioma: A rare case report. J Cancer Res Ther 2015;11:1022.  Back to cited text no. 4
    




 

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