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ORIGINAL RESEARCH REPORT
Year : 2012  |  Volume : 9  |  Issue : 2  |  Page : 18-21

Albinism and the eye in a Sub-Saharan cosmopolitan city


Guinness Eye Centre, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria

Correspondence Address:
Professor F B Akinsola
Department of Ophthalmology, Guinness Eye Centre, Lagos University Teaching Hospital, Idi-Araba, Lagos
Nigeria
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Source of Support: None, Conflict of Interest: None


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Purpose: To evaluate the ocular features of albinism seen in Lagos University Teaching Hospital (LUTH) and Lagos State University Teaching Hospital (LASUTH),Lagos. Study Design: A retrospective study Methods: The case-notes of ocular or oculo-cutaneous albinism patients who presented between January 2004 and December 2008, at Guinness Eye Centre, LUTH, and Eye clinic(LASUTH), Ikeja were reviewed. Results: One hundred and eighteen cases, 74 (62.7%) males and 44 (37.3%) females were seen. There was a male preponderance, male: female ratio of 1.7:1. Ages ranged between 3 months to 56 years. There was positive family history of albinism in 74 (62.7%) and negative family history in 44 (37.3%) patients. Thirteen (11.0%) patients were diagnosed as ocular, while 105 (89.0%) had oculo-cutaneous albinism. Of the 13 with ocular albinism, 10 (76.9%) were males and 3 (23.1%) females (male: female ratio of 3.3:1), while of the 105 with oculo-cutaneous albinism, 59 (56.2%) were males and 46 (43.8%) females (male: female ratio of 1.3:1). Thirty-seven of those with oculo-cutaneous albinism clinically appeared to be tyrosinase positive, and 68 tyrosinase negative. Conclusion: Albinism affects the entire individual including the eye and most features found in this study compare favorably with findings of other authors.


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